
Back when I was first planning my AT hike,
I outlined my completely rational fear of Ixodes scapularis - aka the Deer Tick, aka the Black Legged Tick - The most common vector for Lyme disease. I had explored various strategies to avoid having those nasty hitchhikers latch on to me, and decided to use a combination of deet, and clothing treated with permethrin by Insect Shield. Such clothing protects one from insects thru 70 washings, vice do-it-yourself treatments which last 2-6 weeks, and 6 launderings.
Several major manufacturers of outdoor clothing offer such clothing, but I couldn't find any at my local outfitters. I turned to online vendors, and I outfitted myself with an ExOfficio Bugs-away Halo shirt and a pair of Columbia Bug Shield Cargo Pants - Both utilized Insect Shield treatment. I wore those thru several sections of the AT and experienced no ticks, nor any mosquito bites on areas covered by the fabric. I did have a tick latch on to my sock and crawl down inside.
I hadn't heard of Insect Shield treated socks ...